Virpi Talman Selected Research

isophthalate (isophthalic acid)

1/2022	Protein Kinase A-Mediated Effects of Protein Kinase C Partial Agonist 5-(Hydroxymethyl)Isophthalate 1a3 in Colorectal Cancer Cells.
1/2020	Pharmacological Protein Kinase C Modulators Reveal a Pro-hypertrophic Role for Novel Protein Kinase C Isoforms in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
5/2018	Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer.
5/2014	Evidence for a role of MRCK in mediating HeLa cell elongation induced by the C1 domain ligand HMI-1a3.

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Virpi Talman Research Topics

Disease

6	Neoplasms (Cancer) 01/2022 - 07/2009
2	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 05/2018
2	Hypertrophy 01/2020 - 12/2019
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Fibrosis (Cirrhosis) 01/2021
1	Myocardial Infarction 01/2020
1	Atherosclerotic Plaque (Atheroma) 01/2020
1	Heart Failure 01/2020
1	Cardiomegaly (Heart Hypertrophy) 01/2020
1	Cardiotoxicity 01/2020
1	Alzheimer Disease (Alzheimer's Disease) 08/2016
1	Infarction (Infarctions) 01/2016
1	Myotonic Dystrophy (Dystrophia Myotonica) 05/2014
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/2014
1	Carcinoma (Carcinomatosis) 07/2013
1	Neuroblastoma 07/2013
1	Cognitive Dysfunction 07/2013

Drug/Important Bio-Agent (IBA)

7	Protein Kinase CIBA 01/2022 - 07/2009
4	Phosphotransferases (Kinase)IBA 01/2022 - 07/2013
4	isophthalate (isophthalic acid)IBA 01/2022 - 05/2014
4	Pharmaceutical PreparationsIBA 01/2020 - 05/2014
3	bis(3-trifluoromethylbenzyl) 5-(hydroxymethyl)isophthalateIBA 01/2022 - 07/2013
2	Protein Isoforms (Isoforms)IBA 01/2021 - 01/2020
2	Peptides (Polypeptides)IBA 05/2020 - 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 01/2022
1	Threonine (L-Threonine)FDA Link 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2022
1	Peptide Hydrolases (Proteases)FDA Link 05/2020
1	Prostate-Specific Antigen (Semenogelase)IBA 05/2020
1	AntigensIBA 05/2020
1	Cytotoxins (Cytolysins)IBA 05/2020
1	EstersIBA 05/2020
1	Dextrans (Dextran)FDA Link 01/2020
1	Atrial Natriuretic Factor (ANF)IBA 01/2020
1	2- (1- (3- dimethylaminopropyl)- 5- methoxyindol- 3- yl)- 3- (1H- indol- 3- yl)maleimideIBA 01/2020
1	Endothelin-1 (Endothelin 1)IBA 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	MitogensIBA 01/2020
1	U 0126 (UO 126)IBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 12/2019
1	E2F Transcription FactorsIBA 05/2018
1	GalactosidasesIBA 05/2018
1	AndrogensIBA 05/2018
1	ELAV ProteinsIBA 08/2016
1	Proteins (Proteins, Gene)FDA Link 05/2014
1	protein kinase DIBA 05/2014
1	Monomeric GTP-Binding ProteinsIBA 05/2014
1	LigandsIBA 07/2013

Therapy/Procedure

2	Therapeutics 01/2022 - 01/2021